Repeat Late GDM Testing and Cesarean Delivery Rates

Starting soon · Not applicable

Conditions studied: Large for Gestational Age (LGA), Pregnancy

In brief

The goal of this randomized trial is determine if re-testing for gestational diabetes in the third trimester after an ultrasound measurement of estimated fetal weight (EFW) or abdominal circumference greater than 90%ile decreases cesarean delivery rate, and to evaluate the optimal method of re-testing. The main question it aims to answer is: Does repeat testing for gestational diabetes and management of hyperglycemia decrease the cesarean delivery rate in fetuses measuring \>90%ile by estimated fetal weight (EFW) or abdominal circumference (AC) on ultrasound in the third trimester. Participants will be randomized into two groups: Group 1 will undergo a repeat glucose tolerance test (GTT) with blinded continuous glucose monitor (CGM) and group 2 will have no intervention. Participants in group 1 will receive nutrition counseling as this would be standard in patients at high risk for gestational diabetes.

Key facts

Study ID

NCT07708129

Run by

Shauna F. Williams, MD

People needed

144

Starts

2026-08-01

Expected to finish

2028-05-31

Last updated by the study team

2026-07-16

Who can join

Age: 18 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Gestational age 30 weeks 0 days and 36 weeks 6 days
• Ultrasound with estimated fetal weight or abdominal circumference greater than 90th%ile
• Age 18-50 years old.

You may not qualify if…

• Previously diagnosed gestational diabetes or pre-gestational diabetes
• Multiple gestation
• Previous cesarean delivery
• Any condition precluding vaginal delivery (placenta previa/placenta accreta spectrum disorders, vasa previa, prior uterine surgery with contraindication to vaginal delivery)
• Suboptimal dating (based on US >22wk gestation)
• Contraindication to glucose tolerance test

Full record on ClinicalTrials.gov

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