The Effect of Early Intervention on the Incidence of Posttraumatic Stress Disorder After Intensive Care Hospitalization Due to Sepsis

Recruiting now · Not applicable

Conditions studied: PTSD - Post Traumatic Stress Disorder, Sepsis, ICU

In brief

In recent years, the survival rate among intensive care patients has improved due to advancements in diagnosing severe infections and the use of broad-spectrum antibiotics. However, many survivors face long-term complications, known as Post-Intensive Care Syndrome (PICS), including physical, cognitive, and psychological impairments such as post-traumatic stress disorder (PTSD), anxiety, and depression. Approximately 9-27% of ICU survivors develop these symptoms, particularly those hospitalized due to sepsis. Common risk factors include traumatic hospital experiences, delirium, and extended mechanical ventilation. Despite the prevalence of these issues, most medical centers lack structured models for screening and early intervention, highlighting the need for evaluations of early intervention strategies to support at-risk patients post-discharge and improve their quality of life.

Key facts

Study ID: NCT07707765
Run by: Barzilai Medical Center
People needed: 60
Starts: 2026-07-01
Expected to finish: 2026-12-31
Last updated by the study team: 2026-07-17

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Discharged from ICU due to sepsis
Age over 18 years old

You may not qualify if…

Age under 18 years old
Lack of consent
Dementia/ mental retardation or any other condition due to which the patient cannot fill the questionnaires or participate in the psychiatric interview.
A cute psychosis or other psychiatric condition nesiccating psychiatric treatment.

Where it is running

Barzilai Medical Center — Ashkelon, Israel (enrolling)

Full record on ClinicalTrials.gov

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