Effect of Theravex Tissue Care on Implant Stability
Starting soon · Not applicable
Conditions studied: Immediate Dental Implant Placement
In brief
The aim of this randomized clinical trial is to evaluate the clinical and radiographic outcomes of using Bone Bioactive Liquid (Theravex) compared to Xenograft and a combination therapy (Theravex + Xenograft) during immediate implant placement in the esthetic zone. When a tooth is extracted and replaced immediately with a dental implant, bone grafting is often necessary to fill the gap (jumping distance) between the implant and the surrounding bone socket to support tissue healing and maintain facial contour. Participants requiring immediate implant placement will be randomly assigned into three groups: Group 1: Immediate implant placement using Bone Bioactive Liquid (Theravex). Group 2: Immediate implant placement using Xenograft alone. Group 3: Immediate implant placement using Combination Therapy (Theravex + Xenograft). The primary outcomes will evaluate implant stability, bone dimensional changes, and soft tissue response around the implants over the follow-up period.
Key facts
- Study ID
- NCT07707388
- Run by
- Ain Shams University
- People needed
- 30
- Starts
- 2026-11-12
- Expected to finish
- 2027-09-08
- Last updated by the study team
- 2026-07-16
Who can join
Age: any. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patient requires extraction of a single failing or non-restorable maxillary anterior tooth or premolar.
- Presence of an intact buccal bone plate (Socket Type I) with a horizontal peri-implant jumping gap ≥ 2 mm.
- The implant can be placed in an ideal 3-D position with an intraoperative primary stability target of ≥ 35 Ncm.
- Patient is in good general health with no systemic contraindications to implant surgery.
- Patient is cooperative and available for the entire 6-month follow-up period
You may not qualify if…
- Pregnant and lactating females.
- Heavy smokers (smoking ≥ 10 cigarettes per day).
- Patients with poor oral hygiene.
- Patients with occlusal or malalignment problems.
- Patients with parafunctional habits (e.g., bruxism).
Where it is running
- Faculty of Dentistry - Ain Shams University — Cairo, Egypt
Full record on ClinicalTrials.gov
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