BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)

Recruiting now

Conditions studied: Aging, Cellular Senescence, Biomarkers / Blood, Age-Related Diseases, Frailty

In brief

Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100. Centenarians represent a unique biological model of extreme longevity, often exhibiting delayed onset of age-related diseases and preserved functional capacity. This study aims to establish an intergenerational cohort of centenarians in Navarra (Spain) to investigate the biological, clinical, environmental, and lifestyle factors associated with extreme longevity. By integrating multidimensional data-including clinical assessments, functional and cognitive measures, and biological markers-this study seeks to improve understanding of aging mechanisms and identify potential determinants of healthy aging.

Key facts

Study ID

NCT07707297

Run by

Fundacion Miguel Servet

People needed

333

Starts

2026-02-04

Expected to finish

2027-12-31

Last updated by the study team

2026-07-16

Who can join

Age: 100 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals aged ≥100 years
• Residents of Navarre, Spain

You may not qualify if…

• Clinical decompensation within the last month, including hemodynamic instability, acute illness, or hospitalization;
• End-of-life condition, defined as a clinical state of irreversible deterioration with a life expectancy of days to weeks, as determined by a physician.

Where it is running

• Navarrabiomed — Pamplona, Navarre, Spain (enrolling)

Full record on ClinicalTrials.gov

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