Treatment of Mandibular Overjet in Children With Maxillary Retrognathism

Starting soon · Not applicable

Conditions studied: Maxillary Retrognathism, Children, Treatment, Class III Malocclusion

In brief

The project involves a 10-year prospective longitudinal cohort multicentre study where orthodontic treatment and treatment effect is followed in children with Cl III due to maxillary retrognathia who undergo standardized orthodontic interceptive treatment. Standard clinical procedures are followed as usual at each clinic where standard diagnostic and follow up materials are taken before treatment, after treatment and follow ups after 5 and 10 years. The project will not introduce or test new treatment modalities, additional procedures or behavioural regulation in relation to normal clinical practice or new medical devices. The standard diagnostic and follow up materials in each clinic include examination of the dentition, occlusion, craniofacial morphology, and orofacial function. The analyses are based on the following standardized registration methods which are carried out on all the patients. Information from the patient record is included. The patient related outcome measurements will be assessed by five different questionnaires. No biological material is collected for the project.

Key facts

Study ID

NCT07706400

Run by

Malmö University

People needed

180

Starts

2026-07-31

Expected to finish

2038-07-31

Last updated by the study team

2026-07-15

Who can join

Age: 9 and older, up to 12. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Mandibular overjet due to maxillary retrognathia (Overjet </= 0 mm)
• Age 9-12 years
• Informed consent from parents/guardians

You may not qualify if…

• Mandibular overjet mainly due to mandibular prognathism
• Known general and/or craniofacial syndromes/diseases
• Adenoid vegetations, hypertrophic tonsils and significantly reduced air passage through nose (mouth breathing), which must be primarily treated
• Functional disorders in muscles and jaw joints, which must be primarily treated

Where it is running

• University of Copenhagen — Copenhagen, Denmark, Denmark
• Faculty of Odontology — Malmö, Skåne County, Sweden
• Malmö University — Malmö, Skåne County, Sweden

Full record on ClinicalTrials.gov

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