Virgin Coconut Oil Versus Chlorhexidine Mouthwash in Non-Surgical Periodontal Therapy of Periodontitis Patients. A Randomized Controlled Clinical Trial With Biochemical Assessment.
Starting soon · Not applicable
Conditions studied: Stage II Periodontitis
In brief
This randomized controlled clinical trial will evaluate the effect of virgin coconut oil mouthwash compared with chlorhexidine mouthwash as an adjunct to non-surgical periodontal therapy in patients with stage II periodontitis. Participants will receive scaling and root planing, followed by the assigned mouthwash for 30 days. Clinical periodontal parameters, including plaque index, gingival index, bleeding on probing, probing pocket depth, and clinical attachment level, will be recorded. Gingival crevicular fluid samples will also be collected to assess tumor necrosis factor-alpha levels before and after mouthwash use. The study aims to compare the clinical and biochemical effects of the two mouthwashes.
Key facts
- Study ID
- NCT07706387
- Run by
- Ain Shams University
- People needed
- 42
- Starts
- 2026-07-01
- Expected to finish
- 2026-08-01
- Last updated by the study team
- 2026-07-15
Who can join
Age: 30 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 1. Both genders. 2. Age (30-50) years old. 3. Systemically free according to the modified Burkett's health history questionnaire .
- Generalized Periodontitis Stage II . 5. Having at least 20 tooth excluding wisdoms. 6. No history of dental visit in past three months. 7. Participants willing to commit for the entire period of the trial and agreed to sign the written consent after full explanation of the study.
You may not qualify if…
- 1. Smokers. 2. Status of Pregnancy or Contraceptives usage. 3. Allergy to coconut oil . 4. Previous Periodontal treatment within the last 6 months. 5. Antibiotic and/or Anti-inflammatory therapy within the last 6 months.
Where it is running
- Faculty of Dentistry,Ain Shams University — Cairo, Cairo Governorate, Egypt
Full record on ClinicalTrials.gov
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