Intraperitoneal Irrigation of Ondansteron in Combination With Lidocaine in Acute Postoperative Pain

Recruiting now · Phase 1/Phase 2

Conditions studied: Acue Postoperative Pain

In brief

This study, therefore, aimed to investigate the effect of intraperitoneal administration of ondansetron in combination to lidocaine for postoperative pain management in patients undergoing lower abdominal cancer surgery.

Key facts

Study ID

NCT07706348

Run by

Assiut University

People needed

20

Starts

2026-06-01

Expected to finish

2027-10-01

Last updated by the study team

2026-07-15

Who can join

Age: 20 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ASA I-II patients
• scheduled for major lower abdominal cancer surgeries.

You may not qualify if…

• patients with known allergy to the study drugs,
• significant cardiac, respiratory, renal or hepatic disease,
• body mass index (BMI) ≥30 kg/m2;
• allergy to study drugs
• history of opioid use for pain management the time of enrolment or drug addiction,
• who had used benzodiazepine chronically,
• stroke or psychiatric disease that could affect the perception of pain.

Where it is running

• Assiut University - South Egypt Cancer Instiute — Asyut, Egypt (enrolling)

Full record on ClinicalTrials.gov

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