QLESP Block for Pain Control in Robotic Partial Nephrectomy

Starting soon · Not applicable

Conditions studied: Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain, Nerve Block

In brief

The goal of this clinical trial is to learn if an ultrasound-guided nerve block called QLESP works to reduce pain and the need for strong pain medicines after robotic kidney surgery in adults. The main questions it aims to answer are: 1. Does QLESP reduce the total amount of opioid pain medicine participants need in the first 48 hours after surgery? 2. Does QLESP lower pain scores and improve recovery quality after surgery? Researchers will compare participants who receive QLESP block to participants who receive the same numbing medicine injected only at the surgical wound sites. Participants will: 1. Be randomly assigned to receive either QLESP or local wound injection before surgery. 2. Have a patient-controlled pain pump for 48 hours after surgery. 3. Complete pain scores and recovery quality questionnaires at 2, 6, 12, 24, 48, and 72 hours after surgery. 4. Be followed until hospital discharge.

Key facts

Study ID

NCT07704970

Run by

Huazhong University of Science and Technology

People needed

120

Starts

2026-07-20

Expected to finish

2027-03-31

Last updated by the study team

2026-07-16

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Aged 18 to 75 years
• Scheduled for elective robot-assisted partial nephrectomy (RAPN)
• American Society of Anesthesiologists (ASA) physical status I to III
• Body mass index (BMI) 18 to 35 kg/m²
• Voluntarily signed informed consent form Able to understand pain scoring and use of patient-controlled analgesia (PCA)

You may not qualify if…

• Language, communication, or comprehension barriers
• Infection at the intended puncture site
• Coagulopathy or bleeding diathesis
• Known allergy or contraindication to local anesthetics or opioids
• Use of analgesic medications within the past 3 months
• Peripheral neuropathy
• Severe cardiac, hepatic, or renal dysfunction
• Pregnancy or breastfeeding
• Refusal to participate in the study

Where it is running

• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China

Full record on ClinicalTrials.gov

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