Preoperative 3D Magnetic Resonance Elastography for Predicting Surgical Risk in Patients Undergoing Hepatectomy

Starting soon

Conditions studied: Hepatic Cancer, Hepatocellular Carcinoma, Intrahepatic Cholangiocellular Carcinoma, Metastatic Hepatocellular Carcinoma

In brief

How to accurately and safely evaluate regional liver function before hepatectomy remains an important unsolved problem in the surgical management of hepatocellular carcinoma (HCC). We plan to develop a non-invasive, functional 3D-MRE-based method for preoperative regional hepatic functional reserve assessment, and to evaluate its ability to predict surgical risk and postoperative liver failure in patients with HCC undergoing hepatectomy.

Key facts

Study ID: NCT07704203
Run by: Second Affiliated Hospital of Xi'an Jiaotong University
People needed: 150
Starts: 2026-08-01
Expected to finish: 2030-10-01
Last updated by the study team: 2026-07-15

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Age 18-80 years
Pathologically or radiologically confirmed diagnosis of one of the following: hepatocellular carcinoma, intrahepatic cholangiocarcinoma, or liver metastasis (e.g., from colorectal cancer)
Scheduled to undergo curative hepatectomy
Child-Pugh class A or B liver function
Able to tolerate MRI examination
Provision of signed and dated informed consent

You may not qualify if…

Contraindication to MRI (e.g., non-MRI-compatible implants, severe claustrophobia)
Child-Pugh class C liver function
Prior history of liver resection or liver transplantation
Presence of extrahepatic metastasis
Emergency surgery (e.g., due to tumor rupture)
Severe cardiopulmonary or renal dysfunction precluding surgery
Pregnant or breastfeeding women
Unwillingness or inability to comply with study procedures or follow-up

Full record on ClinicalTrials.gov

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