Prevalence and Determinants of Obesity in PKU Patients

Enrolling by invitation

Conditions studied: Phenylketonuria (PKU)

In brief

This observational cross-sectional multicenter study aims to assess the prevalence of overweight and obesity in adult patients with phenylketonuria (PKU) and to identify associated risk factors. Adult PKU patients followed in metabolic centers in Switzerland and Austria will be evaluated using clinical data, laboratory parameters, and standardized questionnaires addressing diet, physical activity, and psychological factors. The study seeks to better understand contributors to weight gain in this population to inform preventive strategies.

Key facts

Study ID

NCT07703020

Run by

Christel Tran

People needed

100

Starts

2026-03-01

Expected to finish

2029-02-01

Last updated by the study team

2026-07-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed diagnosis of phenylketonuria (PKU) by biochemical and/or molecular testing.
• Age ≥ 18 years.
• Ability to provide written informed consent.

You may not qualify if…

• Pregnant or lactating women.
• Inability to follow the study procedures (e.g., due to language barriers).
• Eligible participants who refuse to be informed of any important health concern discovered during the study.
• Investigators, their family members, employees, or anyone with a personal link to the investigator other than a doctor-patient relationship.

Where it is running

• Lausanne University Hospital — Lausanne, Canton of Vaud, Switzerland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.