AI-Assisted Written Information in Chronic Anal Fissure

Starting soon · Not applicable

Conditions studied: Chronic Anal Fissure

In brief

This single-center, prospective, 1:1 randomized, parallel-group controlled superiority trial compares standard verbal counseling with AI-assisted written patient information in adults with primary chronic anal fissure receiving initial medical/conservative treatment. The primary objective is to determine whether AI-assisted written information improves complete treatment adherence at day 14. Secondary objectives include pain and discomfort outcomes, Patient Global Impression of Change, HEMO-FISS-QoL change, stool form change, additional healthcare visits, transition to interventional treatment, and patient satisfaction.

Key facts

Study ID

NCT07701811

Run by

Sanliurfa Education and Research Hospital

People needed

220

Starts

2026-07-15

Expected to finish

2026-12-31

Last updated by the study team

2026-07-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older
• Clinical diagnosis of primary chronic anal fissure
• Initial medical/conservative treatment planned at first evaluation
• Ability to read and understand Turkish
• Reachable by telephone
• Provision of written informed consent

You may not qualify if…

• Acute anal fissure
• Suspicion or diagnosis of secondary fissure (including Crohn's disease, tuberculosis, HIV-related lesion, suspected malignancy, or atypical lateral fissure)
• Planned botulinum toxin, surgery, or another interventional treatment
• History of botulinum toxin or surgical treatment for anal fissure within the last 6 months
• Concomitant perianal abscess, fistula, advanced hemorrhoidal disease, or another significant anorectal pathology
• Pregnancy and early postpartum period

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.