Three-Dimensional Bone Augmentation of Severely Atrophied Posterior Mandibular Alveolar Ridges Using Customized-3D Zirconia Barriers Versus Pre-bent Titanium Mesh

Recruiting now · Not applicable

Conditions studied: Mandibular Atrophy

In brief

Zirconia can be considered as an alternative and innovative material suitable for GBR because it has high biocompatibility, together with a scarce tissue integration. Zirconia barriers could be a predictable and alternative barrier material for GBR in terms of (i) biocompatibility, (ii) ease of use and removal, (iii) exposure management, (iv) bone regeneration outcomes.

Key facts

Study ID

NCT07700095

Run by

Hams Hamed Abdelrahman

People needed

16

Starts

2024-08-03

Expected to finish

2026-09-01

Last updated by the study team

2026-07-13

Who can join

Age: 20 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients are systemically medically free according to the American Society of Anesthesiologists (ASA) considered as ASA I.
• Ability to maintain good oral hygiene as evidenced in recall visits.
• patients who had a partial or completely edentulous alveolar ridge with apparent 3D defect following teeth loss.
• All patients were free from any local or general disease that may interfere with bone healing and had no history of previous grafting procedure at the designated edentulous ridge.
• The ridge had to exhibit severe vertical and horizontal (3D) alveolar ridge deficiency with alveolar ridge height less than 7 mm from the alveolar crest to the inferior alveolar canal and width less than 5 mm which was firstly measured by CBCT, or a clinically apparent increase in inter-arch space relative to the adjacent natural teeth.
• Pre-operative clinical assessment of soft tissue coverage was done to cover the graft and its membrane, in addition to assessment of occlusion and inter-arch distance should allow for the graft, membrane, implan and the future prosthesis.

You may not qualify if…

• Smoker (> 25 cigarettes/ day).
• Patients undergoing radiotherapy or chemotherapy
• Patients having infection or local lesions in the area of surgery.
• Patients with diabetes mellitus or bone diseases which may compromise the results.
• Patient with poor oral hygiene or active periodontal disease.
• Patient with limited mouth opening.
• Participation in other clinical trials

Where it is running

• Kafr El-sheikh University — Kafr Elsheikh, Egypt (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.