Comparative Evaluation of Direct Pulp Capping Between Deep and Extremely Deep Caries in Mature Permanent Mandibular Molars .

Recruiting now · Not applicable

Conditions studied: Reversible Pulpitis, Deep Caries, Extremely Deep Caries

In brief

The aim of the study is to compare the clinical and radiographic outcomes of direct pulp capping for deep and extremely deep caries in mature permanent mandibular molars with reversible pulpitis. Primary objective of the study is to evaluate the clinical and radiographic success of direct pulp capping for deep and extremely deep caries in mature permanent mandibular molars with reversible pulpitis. Secondary objective of the study is to evaluate and compare postoperative pain following direct pulp capping for deep and extremely deep caries in mature permanent mandibular molars with reversible pulpitis. Subjects of age group 18 - 40 yrs will be included and divided into two groups 1) Permanent mature molars with deep carious lesion 2) Permanent mature molars with extremely deep carious lesion.

Key facts

Study ID

NCT07696702

Run by

Postgraduate Institute of Dental Sciences Rohtak

People needed

130

Starts

2026-04-29

Expected to finish

2028-04-28

Last updated by the study team

2026-07-28

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The patient should be 18-40 years of age.
• Patients with deep and extremely deep caries in permanent mandibular molars.
• Deep caries lesion -Reaching the inner quarter of dentine on radiograph
• Extremely deep caries lesion - Caries penetrating the entire thickness of dentin on radiograph.
• Reversible pulpitis will be diagnosed clinically based on discomfort experienced by the participant when a stimulus such as cold or sweet is applied and goes away within a couple of seconds following removal of stimulus, with no significant radiographic changes in the periapical region of the suspect tooth and pain experienced is not spontaneous.
• Tooth should give positive response to pulp sensibility testing.
• Bleeding can be controlled with in 8 minutes.
• Radiographic finding of periapical index (PAI) score ≤2.
• Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).

You may not qualify if…

• Teeth with immature roots.
• Internal/external resorption.
• Patient experience spontaneous pain.
• Negative response to vitality testing
• No pulp exposure after complete caries excavation.
• Signs of pulpal necrosis, insufficient bleeding after pulp exposure, sinus tract, swelling.
• Bleeding could not be controlled in 8 minutes.
• Pregnant women
• Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency diseases , infectious diseases, kidney or liver, migraine)

Where it is running

• PGIDS , Rohtak — Rohtak, Haryana, India (enrolling)

Full record on ClinicalTrials.gov

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