Effects, Metabolic Mechanisms and Predictors of Response to Acupuncture in Treating Psychoneurological Symptoms Among Breast Cancer Survivors

Starting soon · Phase 3 · Has a placebo group

Conditions studied: Breast Cancer

In brief

The purpose of this study is to examine the effect, mediators and predictors of treatment response of acupuncture in treating the psychoneurological symptom cluster (pain, fatigue, sleep disturbance) among breast cancer survivors.

Key facts

Study ID

NCT07695948

Run by

University of Illinois at Chicago

People needed

252

Starts

2026-09-01

Expected to finish

2031-08-31

Last updated by the study team

2026-07-13

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• ≥ 18 years of age
• With histologically confirmed Stage 0-III ER/PR-positive HER2-negative breast cancer
• Currently receiving adjuvant endocrine therapy
• Completed their primary cancer treatment (e.g., surgery, radiotherapy, chemotherapy) at least 3 months prior to recruitment
• Acupuncture-naïve
• Have self- reported pain, fatigue, and sleep disturbance in the last month with an average severity rating ≥ 3 (0-10 numeric rating scale) for at least 2 of the 3 symptoms.

You may not qualify if…

• Taking methylsulfonylmethane or glutathione supplements
• Physically or cognitively unable to complete the study procedures
• Pregnant

Where it is running

• University of Illinois Chicago College of Nursing, — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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