Preventive Potential of Fluoride Sealants in Adolescent Orthodontic Patients

Starting soon

Conditions studied: White Spot Lesions

In brief

The aim of this trial is to investigate the potential of using an adhesive bonding agent that also acts as a fluoride sealant when placing fixed orthodontic appliances in adolescent patients, as an alternative to regular bonding agents. The main question it aims to answer is: \- Does an adhesive fluoride sealant reduce the prevalence of white spot lesions in orthodontic adolescent patients after an observation period of 3 months? Participants who need orthodontic treatment and who agree to take part in this study will have their orthodontic appliance placed using regular adhesive on one side of their upper jaw and fluoride sealant on the other. White spot lesion prevalence will be assessed using the Enamel Decalcification Index (EDI) at baseline and after 3 months.

Key facts

Study ID

NCT07691879

Run by

Sigmund Freud PrivatUniversitat

People needed

40

Starts

2026-09-01

Expected to finish

2027-05-01

Last updated by the study team

2026-07-09

Who can join

Age: 10 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age between 10 and 17 years
• Initiation of fixed orthodontic treatment in the upper jaw
• Presence of all teeth 15-25
• Written consent from patients and legal guardians

You may not qualify if…

• Pre-existing white spot lesions
• Active carious lesions
• Structural enamel defects
• Systemic diseases affecting oral health
• Vestibular restorations in the anterior region
• Little Index > 9

Full record on ClinicalTrials.gov

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