A Study of a New PET Scanner in People With Cancer

Recruiting now

Conditions studied: Non Small Cell Lung Carcinoma NSCLC, Head and Neck Cancer, Prostate Cancer

In brief

The researchers are doing this study to test the capabilities of a new total-body PET scanner called the Biograph Vision Quadra. The researchers want to learn whether this scanner can produce better PET/CT images and provide more useful imaging information than standard PET/CT scanners.

Key facts

Study ID

NCT07690917

Run by

Memorial Sloan Kettering Cancer Center

People needed

90

Starts

2026-06-30

Expected to finish

2029-06-01

Last updated by the study team

2026-07-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Eligibility Criteria for objective #1:
• Patients with histologically-confirmed non-small cell lung carcinoma (NSCLC) with a single or multiple lung nodules.
• Patients who are undergoing a planned PET-CT scan at main campus of MSK.
• Patients must be ≥ 18 years old
• Eligibility Criteria for objective #2:
• Patients with disease within the chest, abdomen or pelvis, who could benefit from visualizing the pharmacokinetics of radiotracer uptake within all disease sites simultaneously.
• Patients with metastatic prostate or head and neck cancer.
• Patients with prostate cancer who are undergoing a 68Ga-PSMA or 18F-FDG scan at the main campus of MSK.
• Patients with head and neck cancer who are undergoing a 18F-FDG scan at the main campus of MSK
• Patients must be ≥ 18 years old
• Eligibility Criteria for objective #3:
• Patients with histologically-confirmed cancer from all three groups (lung cancer, head and neck cancer, prostate cancer).
• Patients who are undergoing an 68Ga-PSMA or 18F-FDG or an [18F]-fluormisonidazole PET-CT scan at the main campus of MSK.
• Patients willing to return to the MITS clinc for late imaging session between 2 to 6 hours after the PET radiotracer injection. (In current practice, FDG is imaged between 1 and 1.5 hours post injection, and FMISO is imaged between 2.5 and 3 hours post injection)
• Patients must be ≥ 18 years old

You may not qualify if…

• Patients who suffer from claustrophobia.
• Women who are pregnant or breast-feeding.
• Patients < 18 years of age

Where it is running

• Memorial Sloan Kettering Basking Ridge (Consent Only) — Basking Ridge, New Jersey, United States (enrolling)
• Memorial Sloan Kettering Monmouth (Consent Only) — Middletown, New Jersey, United States (enrolling)
• Memorial Sloan Kettering Bergen (Consent Only ) — Montvale, New Jersey, United States (enrolling)
• Memorial Sloan Kettering Suffolk-Commack (Consent Only) — Commack, New York, United States (enrolling)
• Memorial Sloan Kettering Westchester (Consent Only) — Harrison, New York, United States (enrolling)
• Memorial Sloan Kettering Cancer Center — New York, New York, United States (enrolling)
• Memorial Sloan Kettering Nassau (Consent Only) — Rockville Centre, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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