Noninvasive Artificial Venous Stasis for Reperfusion in STEMI
Recruiting now
Conditions studied: STEMI - ST Elevation Myocardial Infarction
In brief
This prospective, randomized study was designed to evaluate whether the noninvasive artificial venous stasis / RE-START procedure, administered prior to primary percutaneous coronary intervention, increases the frequency of spontaneous coronary reperfusion in the infarct-related artery.
Key facts
- Study ID
- NCT07689591
- Run by
- Firat University
- People needed
- 500
- Starts
- 2026-07-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-07-10
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Having presented within the first 12 hours of symptom onset Being hemodynamically stable (Killip Class I-II)
- STEMI diagnosis confirmed by coronary angiography
- Primary PCI (percutaneous coronary intervention) scheduled
- No pathology in the upper extremity that would prevent cuff application
- Be capable of providing informed consent and provide consent
You may not qualify if…
- Presence of cardiogenic shock (systolic blood pressure < 90 mmHg and Killip Class III-IV)
- Cardiac arrest occurring before or after the procedure
- Need for resuscitation following failed thrombolysis
- History of prior coronary artery bypass surgery
- Concurrent acute aortic dissection
- Venous thromboembolism or pulmonary embolism
- History of an acute infection within the past 7 days
- Chronic kidney disease requiring erythropoietin therapy or currently undergoing hemodialysis
- Presence of liver failure or a hematologic disorder
- Presence of any chronic inflammatory or autoimmune disease
- History of any known malignancy (cancer)
- Current treatment with glibenclamide, corticosteroids, antioxidant vitamins, or cyclosporine at the time of enrollment
- History of chronic (daily) alcohol consumption
- Contraindications to aspirin and/or clopidogrel
- Failure to confirm a STEMI diagnosis via coronary angiography
- Inability to provide informed consent
- Pregnancy
- First 6 months postpartum Conditions in which the administration of thrombolytics is contraindicated
Where it is running
- Firat University — Elâzığ, Elaziğ, Turkey (Türkiye) (enrolling)
- Firat University — Elâzığ, Merkez, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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