Poly-L-lactic Acid (PLLA) Injection for Neck Skin Laxity: A Pilot Study

Starting soon · Not applicable

Conditions studied: Skin Aging, Wrinkles

In brief

Skin aging of the neck commonly leads to wrinkles and skin laxity due to the gradual loss of collagen and structural support in the skin. Although several treatments are available, effective non-surgical options for improving neck skin laxity remain limited. This pilot study aims to evaluate the effectiveness and safety of Poly-L-Lactic acid (PLLA) injections for improving neck skin laxity.

Key facts

Study ID

NCT07689344

Run by

Institute of Dermatology, Thailand

People needed

10

Starts

2026-07-01

Expected to finish

2026-09-01

Last updated by the study team

2026-07-08

Who can join

Age: 30 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Thai male or female participants aged 30-60 years
• Individuals who wish to improve neck skin laxity
• Presence of neck skin laxity grade 1-4 according to the Neck Skin Laxity Scale (NSL scale)

You may not qualify if…

• Pregnant or breastfeeding women
• History of allergy or hypersensitivity to local anesthetics or components of collagen-stimulating substances
• Active autoimmune disease requiring systemic treatment
• History of cosmetic procedures in the neck area, including laser treatment, radiofrequency, or ultrasound-based devices within 6 months prior to treatment
• History of dermal filler injection in the neck area
• History of botulinum toxin injection in the neck area within 6 months prior to treatment

Where it is running

• Institute of Dermatology — Ratchathewi, Bangkok, Thailand

Full record on ClinicalTrials.gov

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