Evaluation of Wear Resistance of CAD/CAM Hybrid Ceramic and Nano-Hybrid Composite Overlays in Endodontically Treated Molars and Their Effect on Natural Antagonist Teeth

Starting soon · Not applicable

Conditions studied: Wear, Occlusal

In brief

This randomized clinical trial aims to to evaluate and compare the 24-month surface wear of the restoration and the surface wear of the opposing natural tooth structure of CAD/CAM Hybrid Ceramic (SHOFU Hard blocks) versus Resin-based Composite (BRILLIANT Crios) overlays, utilizing a digital subtraction methodology (Intraoral Scanner and Geometrical Subtraction Software) in endodontically treated molar teeth.

Key facts

Study ID

NCT07689032

Run by

Cairo University

People needed

24

Starts

2026-07-01

Expected to finish

2028-07-01

Last updated by the study team

2026-07-07

Who can join

Age: 22 and older, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age between 22 and 45 years.
• Low to moderate caries risk.
• Normal occlusion.
• Absence of signs or symptoms of temporomandibular joint (TMJ) disorders.
• Satisfactory oral hygiene.
• Medically fit to receive routine restorative dental treatment.
• Permanent molars.
• Asymptomatic endodontically treated teeth.
• Homogeneous root canal fillings extending 1-2 mm from the radiographic apex.
• Compound cavities.
• Favorable occlusion.
• Presence of both an adjacent tooth and a sound opposing tooth in occlusion

You may not qualify if…

• * Presence of bruxism.
• Poor patient cooperation.
• Inability or unwillingness to attend follow-up appointments.
• Anticipated travel during the study period.
• Poor oral hygiene.
• Chronic or advanced periodontitis.
• Known allergies to any of the materials used in the study.
• Patients who are pregnant or breastfeeding.
• Teeth with <1" mm" of residual wall thickness.
• Deep subgingival cavity margins.
• Severe periodontal problems.
• Radiographic signs of apical pathology.

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.