Monoamine Oxidase B PET/CT in Various MAO-B-Related Disease

Recruiting now

Conditions studied: Parkinson Disease, Parkinson Disease Dementia, Parkinson's Disease and Parkinsonism

In brief

To evaluate the potential usefulness of 18F-FPyCO/SMBT-1 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various MAO-B-related disease patients.

Key facts

Study ID

NCT07685873

Run by

Tianjin Medical University

People needed

200

Starts

2026-06-25

Expected to finish

2029-07-01

Last updated by the study team

2026-07-06

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated PD (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled TSPO PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

You may not qualify if…

• patients with non-malignant lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Where it is running

• The First Affiliated Hospital of University of Science and Technology of China — Hefei, Anhui, China (enrolling)
• Tianjin Medical University General Hospital — Tianjin, Tian, China (enrolling)

Full record on ClinicalTrials.gov

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