Electronic Health Record Augmented LDL-Cholesterol Optimization and Control Via Active Lipid Engagement (EHR-LOCALE): A Quality Improvement Implementation Study

Starting soon · Not applicable

Conditions studied: ACS (Acute Coronary Syndrome), Hyperlipidemia, Dyslipidemia, Low-Density-Lipoprotein-cholesterol Level

In brief

The purpose of this study is to determine whether a proactive, EHR-guided approach helps more individuals reach safe cholesterol levels, improves medication use, and reduces future heart attacks and strokes, compared to usual care. The main question it aims to answer is: • Does the EHR-LOCALE pathway increases the proportion of patients who reach the LDL-cholesterol target of \<1.8 mmol/L at 6 months? Participants in the interventional group receive: * Pharmacist contact * Repeat lipid requisitions * Review of medications, adherence, and side effects * Treatment escalation according to national dyslipidemia guidelines

Key facts

Study ID

NCT07685639

Run by

University of Alberta

People needed

2000

Starts

2026-08-01

Expected to finish

2027-09-01

Last updated by the study team

2026-07-06

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults over the age of 18
• Resident of Alberta
• Individuals hospitalized with an acute coronary syndrome and have undergone coronary angiography.
• Able to participate in follow-up contact if randomized to the intervention arm

You may not qualify if…

• In-hospital mortality

Full record on ClinicalTrials.gov

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