LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement

Starting soon · Not applicable

Conditions studied: Mild Cognitive Impairment

In brief

LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being. This study will develop and evaluate an enhanced multilingual LBM app for community-dwelling, diverse older adults with mild cognitive impairment (MCI) or at risk of MCI and their informal caregivers, including Hispanic/Latino, Asian American (as one of subgroups, Korean), Black or African American, and non-Hispanic White populations. The app provides culturally tailored life story prompts with audio and visual cues to encourage reminiscence and storytelling. The intervention aims to improve quality of life, reduce depressive symptoms and loneliness, and strengthen caregiver-care recipient relationships, with the potential to provide an accessible, non-pharmacological approach to supporting cognitive and emotional well-being.

Key facts

Study ID

NCT07685067

Run by

George Mason University

People needed

168

Starts

2026-08-01

Expected to finish

2028-05-31

Last updated by the study team

2026-07-06

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

Full record on ClinicalTrials.gov

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