Effect of Systemic Vitamin D on Dental Implant Osseointegration

Recruiting now · Not applicable

Conditions studied: Dental Implant, Dental Implant Failed, Vitamin D Deficiency

In brief

The primary goal for any oral implantologist is to obtain satisfactory healing and long-term treatment success. Osseointegration is the key to dental implant success8 and is required to achieve direct structural and functional connection between living bone and the surface of a load-bearing artificial implant, is critical for the long-term success of dental implants. Successful dental implant therapy relies on achieving proper osseointegration, which ensures a stable structural and functional bond between the implant surface and surrounding bone. Although dental implants show a high overall success rate of around 95%.

Key facts

Study ID

NCT07684404

Run by

Future University in Egypt

People needed

10

Starts

2025-11-01

Expected to finish

2026-11-01

Last updated by the study team

2026-07-06

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adults aged 20-60 with diagnosed vitamin D deficiency (<20 ng/mL).
• Edentulous area in the posterior mandible or maxilla.
• No history of previous dental implant failure, metabolic bone diseases, or conditions affecting bone healing.
• Both genders are included

You may not qualify if…

• Severe systemic diseases that could interfere with healing.
• Patients already on vitamin D or calcium supplements.
• Smokers or patients with poor oral hygiene practices.
• Pregnant females

Where it is running

• Future University in Egypt (FUE) — Cairo, New Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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