Clinical Validation of Isothermal Nucleic Acid Amplification Bioassays Modules - GUINEA

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Conditions studied: Ebola Hemorrhagic Fever, Lassa Hemorrhagic Fever

In brief

This study aim to validate the clinical performances of two newly developed isothermal nucleic acid amplification bioassays modules for EBOV and LASV. Two retrospective studies will be conducted using biobanked patient samples such as plasma samples and buccal swabs already collected by the Centre de Recherche en Virologie, Laboratoire des Fièvres Hémorragiques Virales de Guinée (CRV-LFHVG) as part of their surveillance and outbreak activities. The diagnostic sensitivity and specificity of the EBOV and LASV bioassays modules will be compared to the gold-standard reverse transcriptase polymerase chain reaction (RT-PCR) technologies used in the national reference lab.

Key facts

Study ID
NCT07681752
Run by
Institute of Tropical Medicine, Belgium
People needed
150
Starts
2027-01-01
Expected to finish
2027-12-01
Last updated by the study team
2026-07-02

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

You may not qualify if…

Full record on ClinicalTrials.gov

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