Caris Chromoseq Data Collection

Recruiting now

Conditions studied: Acute Myeloid Leukemia (AML), Myelodysplastic (MDS) / Myeloproliferative (MPN) Diseases, Myelodysplatic Syndromes, Myeloproliferative Neoplasm

In brief

The study will collect clinical data on patients who receive the Caris Chromoseq assay for an underlying hematologic malignancy. The assay provides risk stratification for patients with acute myeloid leukemia (AML) myelodysplastic syndrome (MDS), or myeloproliferative neoplasms (MPN). The hypothesis of the study is that Caris Chromoseq compares favorably to conventional cytogenetics, FISH, and NGS analysis in terms of risk stratification capabilities, ease of use, and turnaround time.

Key facts

Study ID

NCT07680868

Run by

Caris Science, Inc.

People needed

300

Starts

2026-07-01

Expected to finish

2029-07-01

Last updated by the study team

2026-07-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• In order to be eligible to participate in this study, an individual must meet all of the following criteria:
• Stated willingness to comply with all study procedures and availability for the duration of the study and has signed consent form
• Subject must be 18 or older
• Subject be diagnosed with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or myeloproliferative neoplasms (MPN)
• Physician must order or plan to order Caris Chromoseq for their patient
• Physicians must order or have ordered conventional cytogenetics, FISH, and NGS testing for AML, MDS, or MPN within the same timeframe of Caris Chromoseq without intervening line of therapy.

You may not qualify if…

• An individual who meets any of the following criteria will be excluded from participation in this study:
• Patient for whom Caris Chromoseq is not being ordered
• Patient is pregnant or lactating
• Patient is not able or willing to provide consent to data collection for this protocol

Where it is running

• Caris Life Sciences — Phoenix, Arizona, United States (enrolling)

Full record on ClinicalTrials.gov

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