Modeling the Early Stages of Autoimmunity Through the Study of Immunological Thrombocytopenic Purpura and Juvenile Lupus
Starting soon · Not applicable
Conditions studied: Immune Thrombocytopenic Purpura ( ITP ), Systemic Lupus Erythematosus (SLE)
In brief
Immunologic thrombocytopenic purpura (ITP) in children is a pre-lupus condition if associated with the presence of anti-nuclear antibodies (ANA), providing a unique model for understanding the natural history of autoimmunity, particularly that of systemic lupus erythematosus (SLE). The investigators will describe the shared and/or unique immunological pathways involved at diagnosis in 70 children with ITP and in 20 children with SLE, and compare them between ITP-ANA- (more often transient), ITP-ANA+ (pre-lupus condition, more often persistent) and SLE
Key facts
- Study ID
- NCT07680010
- Run by
- University Hospital, Bordeaux
- People needed
- 105
- Starts
- 2026-07-01
- Expected to finish
- 2033-10-01
- Last updated by the study team
- 2026-07-17
Who can join
Age: 1 and older, up to 18. Sex: any. Healthy volunteers: accepted.
Where it is running
- Chu de Bordeaux- Groupe Hospitalier Pellegrin - Hôpital des Enfants — Bordeaux, France
- CHU Toulouse - Hôpital des Enfants — Toulouse, France
Full record on ClinicalTrials.gov
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