Study on the Association Between Serrated Polyps and Metachronous Advanced Colorectal Neoplastic Lesions
Starting soon
Conditions studied: Sessile Serrated Lesion, Serrated Polyp
In brief
This study aims to explore the risk factors associated with the development of ACN and same-site ACN in patients with SP, thereby informing the optimization of clinical surveillance strategies
Key facts
- Study ID
- NCT07678788
- Run by
- Changhai Hospital
- People needed
- 750
- Starts
- 2026-06-01
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-07-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patients aged > 18 years;At least one SP detected during the index colonoscopy and pathologically confirmed as TSA or SSL (according to the 2019 WHO classification criteria);Underwent complete polypectomy during the index colonoscopy;Received regular follow-up at Changhai Hospital, with an interval of ≥ 6 months between the index and follow-up colonoscopies;Complete clinical and pathological data.
You may not qualify if…
- Incomplete colonoscopy or failed cecal intubation;Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale (BBPS) score < 6 or a score < 2 in any bowel segment;Withdrawal time < 6 minutes;Diagnosis of hereditary cancer syndromes, such as familial adenomatous polyposis (FAP) or Lynch syndrome;Concurrent inflammatory bowel disease (IBD) or indeterminate colitis;History of colorectal cancer or other malignancies;Incomplete clinical or pathological records.
Full record on ClinicalTrials.gov
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