Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique

Recruiting now · Not applicable

Conditions studied: Nd:YAG Laser, Sclerotherapy, Diode Laser, Reticular Veins, Telangiectasias, CLaCS Technique

In brief

This study aims to compare the efficacy (in terms of vein clearance) and safety of Nd:YAG laser combined with injection sclerotherapy versus diode laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique.

Key facts

Study ID

NCT07678697

Run by

Ain Shams University

People needed

80

Starts

2026-06-01

Expected to finish

2026-12-01

Last updated by the study team

2026-07-01

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 18-60 years.
• Both sexes.
• Presence of reticular veins and/or telangiectasias (CEAP classification C1).
• Fitzpatrick skin types II-V.
• Patients seeking cosmetic treatment.

You may not qualify if…

• Pregnancy or lactation.
• History of deep vein thrombosis.
• Coagulation disorders.
• Allergy to sclerosant agents.
• Active skin infection at treatment site.
• Previous treatment of target veins within 6 months.
• Great saphenous vein or short saphenous vein incompetence.
• Deep venous insufficiency or thrombosis.
• Abnormal venous duplex findings.

Where it is running

• Ain Shams University — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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