Exposome, Pollutants, Biology in the Older Subject: EXPOSAGE
Starting soon · Not applicable
Conditions studied: Aging Disorder
In brief
Numerous factors, both individual and environmental, can influence aging, an individual's health, and their functional status. However, the understanding of the combined impact of lifestyle-related exposures (e.g., physical activity, diet, sleep) (personal external exposome), exposures to pollutants (environmental external exposome), and their biological responses (internal exposome)-in other words, the impact of the "exposome" on healthy aging-remains limited, particularly in characterizing the molecular mechanisms associated with these interactions. Exposome approaches identifying key exposures and molecular mechanisms could lead to a better understanding of how the environment, interacting with health behaviors, can affect functional status. Thus, the objective of this study is i) to evaluate the links between the external exposome, the internal exposome and the health of older and aging individuals, and ii) to identify biological markers associated with a vulnerable health status in older and aging individuals.
Key facts
- Study ID
- NCT07678528
- Run by
- Centre Hospitalier Universitaire de Nice
- People needed
- 400
- Starts
- 2030-09-01
- Expected to finish
- 2031-09-01
- Last updated by the study team
- 2026-07-01
Who can join
Age: 55 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Aged 55 or over
- Affiliated with or beneficiaries of a social security scheme
- Signed the informed consent form •-Persons residing in one of the following municipalities : Antibes, Le Bar-sur-Loup, Berre-les-Alpes, Beuil, Blausasc, Breil-sur-Roya, Cabris, Cannes, Carros, Clans, Contes, Drap, L'Escarène, Escragnolles, Fontan, La Gaude, Gilette, Grasse, Lantosque, Levens, Nice, Peillon, Peymeinade, Saint-André-de-la-Roche, Saint-Etienne-de-Tinée, Sospel, Tourrettes-sur-Loup, Vence, Tende
You may not qualify if…
- patients currently undergoing intensive drug treatment, including chemotherapy
Where it is running
- CHU de Nice - Hopital de Cimiez — Nice, France
Full record on ClinicalTrials.gov
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