Effect of Blood Flow-restricted Exercise Frequency on Strength Recovery Following Incomplete SCI

Enrolling by invitation · Not applicable

Conditions studied: Spinal Cord Injury

In brief

The goal of this clinical trial is to determine the effect of treatment frequency on the physical recovery of adults with incomplete spinal cord injury. The treatment will last for eight weeks and will occur either either two or three times weekly. The main research questions are: 1. How do changes in muscle strength compare between participants who receive eight weeks of blood flow-restricted exercise two times vs. three times weekly? 2. How do changes in the level of independence performing a selected functional task compare between participants who receive eight weeks of treatment two times vs. three times weekly? 3. How do changes in the perceived exertion needed to perform a functional task compare between participants who receive eight weeks of treatment two times vs. three times weekly? The researchers will compare people receiving treatment two vs. three times per week to see if they differ in the amount of change seen in muscle strength, level of independence performing a functional task requiring use of the targeted muscle group, and/or perceived exertion required to perform the functional task. Participants will: 1. complete three pre-treatment evaluation sessions to establish muscle strength, level of independence performing a functional task, and perceived exertion required to perform a functional task. 2. perform four sets of 20 muscle contraction repetitions of blood flow-restricted exercise on the left and right sides of the body using the targeted muscle group either two times or three times weekly depending on treatment group assignment. 3. complete three post-treatment evaluation sessions to establish muscle strength, level of independence performing a functional task, and perceived exertion required to perform a functional task.

Key facts

Study ID

NCT07678437

Run by

Quality Living, Inc.

People needed

20

Starts

2026-07-15

Expected to finish

2027-07-01

Last updated by the study team

2026-08-05

Who can join

Age: 19 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• A current client receiving treatment for a spinal cord injury at Quality Living, Inc.

You may not qualify if…

• Does not speak English
• Can not follow commands
• Recent history of deep vein thrombosis, autonomic dysreflexia, orthostatic hypotension, or cardiovascular disease

Where it is running

• Quality Living, Inc. — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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