Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation

Recruiting now · Not applicable

Conditions studied: Depigmentation Treatment, Depigmentation

In brief

This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.

Key facts

Study ID

NCT07677826

Run by

Al-Azhar University

People needed

20

Starts

2026-03-02

Expected to finish

2026-12-20

Last updated by the study team

2026-07-01

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Systemically healthy patient of both genders aged from 18-45 years.
• Presence of bilateral physiologic gingival pigmentation in the anterior maxillary or mandibular region DOPI grades III-IV only.
• Good oral hygiene.
• Thick gingival phenotype.

You may not qualify if…

• Patient clinically diagnosed with periodontitis.
• Pregnant or lactating females.
• Patient with previous treatment of gingival hyperpigmentation.
• History of hypersensitivity to any study material.
• Patients who are active or previous smokers.

Where it is running

• Faculty of dental medicine for girls? ALAZHAR University, Cairo, egypt — Nāşir, Egypt (enrolling)

Full record on ClinicalTrials.gov

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