Interventions to Enhance Quadriceps Output After ACLR

Starting soon · Not applicable

Conditions studied: ACL

In brief

The investigators are interested in determining what treatments are effective in reducing inhibition after anterior cruciate ligament (ACL) surgery and helping people increase quadriceps strength. Two interventions that are often used clinically are neuromuscular electrical stimulation (NMES) and vibration. This is a study of how effective these treatments are, whether they work the same for everyone, and if one is better than the other. 22 participants will be enrolled and on study for 2 to 3 weeks.

Key facts

Study ID

NCT07674784

Run by

University of Wisconsin, Madison

People needed

22

Starts

2026-08-01

Expected to finish

2027-08-01

Last updated by the study team

2026-07-13

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have undergone ACLR within the previous 4 months
• Are at least 2 months post-ACLR

You may not qualify if…

• A history of ACLR on both legs
• Since the most recent ACLR:
• secondary lower extremity surgery
• leg or foot fracture
• Unable to walk without an assistive device
• Pain of greater than 5/10 during quadriceps strengthening exercises with the surgical limb
• Cannot achieve 90 degrees of knee flexion with the surgical limb
• People with contraindications to NMES
• Anyone who had a previous skin reaction to NMES or attempted but could not tolerate NMES
• Peripheral neuropathy or other neurological conditions

Where it is running

• UW Health — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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