Standard Versus Novel RFA for Chronic Knee Pain in Osteoarthritis
Starting soon · Not applicable
Conditions studied: Osteoarthritis, Knee
In brief
Brief Summary The goal of this pilot study is to evaluate the feasibility and safety of conducting a randomized comparison of two standard-of-care knee radiofrequency ablation (RFA) techniques in adults with chronic knee pain related to knee osteoarthritis. Participants who are already scheduled to receive knee RFA as part of their standard clinical care will be randomized to receive either a standard 3-target (standard) RFA protocol or a 6-target (novel) RFA protocol. The main purpose of this pilot study is to determine whether a future larger randomized trial comparing these two RFA approaches is feasible and safe to conduct. Participants will complete questionnaires about pain, knee function, and stiffness at baseline and at follow-up timepoints for up to 12 months after the RFA procedure. Preliminary pain relief outcomes will also be explored to help inform the design of a future definitive trial. Participants already scheduled for a knee RFA procedure as part of their standard of care for pain related to knee osteoarthritis will answer online survey questions about their pain for up to 12 months.
Key facts
- Study ID
- NCT07674082
- Run by
- Lawson Research Institute of St. Joseph's
- People needed
- 24
- Starts
- 2026-07-20
- Expected to finish
- 2029-08-20
- Last updated by the study team
- 2026-07-06
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Any patient with knee osteoarthritis receiving knee RFA.
- Stable pain medications for past 1 month.
- Able to speak English.
You may not qualify if…
- Scheduled for knee surgery within 6 months following RFA procedure.
- Participating in another study that the Principal Investigator or Co-Investigators deem will interfere with the interpretation of the results.
Full record on ClinicalTrials.gov
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