Autologous Platelet Concentrates on the Healing of Extraction Sockets

Starting soon · Not applicable

Conditions studied: Medication-related Osteonecrosis of the Jaw

In brief

This study will evaluate the effect of A-PRF, a second-generation APC, on early wound healing in high-risk MRONJ patients following dental extractions, utilising advanced non-invasive methods to assess and associate molecular and blood flow changes during early healing. The early healing events of the post-extraction socket will also be characterised in terms of volumetric changes in relation to intra-oral thermographic changes, blood flow changes, in tandem with clinical measures of soft tissue healing and post-operative pain assessment. The early healing events will be analysed up to 15 days, and the final recall will be 180 days after extraction.

Key facts

Study ID

NCT07673848

Run by

Queen Mary University of London

People needed

44

Starts

2026-06-01

Expected to finish

2029-06-01

Last updated by the study team

2026-06-29

Who can join

Age: 25 and older. Sex: any. Healthy volunteers: not accepted.

Full record on ClinicalTrials.gov

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