Postoperative Pain After Pediatric Adenotonsillectomy With Ketorolac or Ibuprofen

Starting soon

Conditions studied: Sleep, Pediatrics, Adenotonsillectomy

In brief

This prospective observational study will evaluate postoperative pain after outpatient pediatric adenotonsillectomy in adolescents prescribed either acetaminophen with ibuprofen or acetaminophen with oral ketorolac after discharge, based on the prescribing preference of the otolaryngology surgeon. Participants will complete text-message surveys after discharge to assess pain severity, medication administration, and functional recovery for up to 14 days.

Key facts

Study ID

NCT07672418

Run by

Baylor College of Medicine

People needed

200

Starts

2026-06-24

Expected to finish

2027-06-30

Last updated by the study team

2026-06-29

Who can join

Age: 13 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Scheduled for outpatient adenotonsillectomy Age 13-18 years ASA physical status I-III Patient or parent has access to a phone with text-messaging capability Patient assent Parent or legal guardian consent

You may not qualify if…

• Inpatient admission or planned 23-hour observation Known hematologic condition or prior bleeding disorder Current anticoagulant use Known or suspected chronic kidney disease or solitary kidney Known or suspected liver disease or prior liver transplant Known or suspected mitochondrial disease or genetic anomaly Inability to self-report pain History of gastrointestinal ulcer or bleeding Allergy to acetaminophen, ibuprofen, or ketorolac Non-English or non-Spanish speaking Chronic pain or condition requiring frequent routine NSAID use Patient refusal Parent or guardian refusal

Where it is running

• Baylor College of Medicine/ Texas Childrens Hospital — Houston, Texas, United States

Full record on ClinicalTrials.gov

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