Period Pills for Menstrual Regulation: A New Reproductive Health Option

Recruiting now · Phase 4

Conditions studied: Menstrual Regulation, Menstrual Health Intervention

In brief

The Period Pills Study is a prospective observational study among people who decide to use a combination of mifepristone and misoprostol for menstrual regulation.

Key facts

Study ID

NCT07671989

Run by

University of California, San Francisco

People needed

100

Starts

2026-06-22

Expected to finish

2027-05-31

Last updated by the study team

2026-06-26

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Be 18 years old or older
• Read and speak English
• Know the date of their last menstrual period within 2 days
• Have a period that is late by up to 21 days
• Must have had regular periods in the last 4 months
• Does not want to be pregnant
• Does not want to verify pregnancy status
• Understand that if they are pregnant, the pills will end their pregnancy
• Does not have contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

You may not qualify if…

• Under 18 years old
• Does not read and speak English
• Does not know the date of their last menstrual period within 2 days
• Has not had regular periods in the last 4 months
• Wants to be pregnant
• Wants to verify pregnancy status
• Does not display understanding that if they are pregnant, the pills will end their pregnancy
• Has any contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

Where it is running

• Roanoke Health Center — Roanoke, Virginia, United States (enrolling)
• UCSF Advancing New Standards in Reproductive Health (ANSIRH) — Oakland, California, United States

Full record on ClinicalTrials.gov

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