Mechanical Power During Different Ventilation Modes in Laparoscopic Surgery
Recruiting now · Not applicable
Conditions studied: Laparoscopic Cholecystectomy, Mechanical Ventilation, Ventilator-Induced Lung Injury
In brief
This study investigates how different breathing machine (ventilator) settings affect the energy delivered to the lungs during surgery. Mechanical power is a measure of this energy, and high levels can sometimes lead to lung irritation. In clinical practice, a mode called Pressure-Regulated Volume Control (PRVC) is often used because it lowers the "peak" pressure in the airways, which is generally thought to be safer. However, doctors have noticed that even though the peak pressure goes down in PRVC mode, the total mechanical power displayed on the monitor might actually increase compared to the standard Volume-Controlled Ventilation (VCV) mode. In this study, patients undergoing gallbladder surgery will be monitored using both ventilation modes in a random order. The researchers will compare the machine-calculated mechanical power for both modes to see if the perceived benefit of lower peak pressure in PRVC actually results in lower overall energy transfer to the lungs.
Key facts
- Study ID
- NCT07670494
- Run by
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- People needed
- 80
- Starts
- 2026-07-01
- Expected to finish
- 2026-08-12
- Last updated by the study team
- 2026-07-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients undergoing elective laparoscopic cholecystectomy surgery.
- Patients between 18 and 75 years of age.
- American Society of Anesthesiologists (ASA) physical status I, II or III.
- Body Mass Index (BMI) between 18.5 and 35 kg/m².
- Voluntary written informed consent for participation.
You may not qualify if…
- History of significant chronic obstructive pulmonary disease (COPD) or asthma.
- Previous lung resection or major thoracic surgery.
- Heavy smokers (more than 20 cigarettes per day).
- Presence of spontaneous breathing effort during mechanical ventilation.
- Conversion from laparoscopic surgery to open surgery during the procedure.
- Emergency surgery cases.
- Known pregnancy.
Where it is running
- Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital — Yenimahalle, Ankara, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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