Different Pressure Tissue Flossing Combined With Exercise for Chronic Ankle Instability

Starting soon · Not applicable

Conditions studied: Chronic Ankle Instability, Ankle Instability

In brief

This study will evaluate whether tissue flossing with different pressure levels, when combined with exercise training, improves ankle function in young adults with chronic ankle instability. Forty-eight participants will be randomly assigned to one of three groups: a control exercise group, a 150 mmHg tissue flossing plus exercise group, or a 200 mmHg tissue flossing plus exercise group. All groups will complete the same 6-week rehabilitation program, three times per week. Outcomes will be assessed at baseline and after the intervention, and long-term follow-up data will also be collected.

Key facts

Study ID

NCT07667816

Run by

Chengdu Sport University

People needed

48

Starts

2026-07-01

Expected to finish

2027-05-01

Last updated by the study team

2026-06-25

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Young adults aged 18 to 30 years.
• History of at least one recurrent ankle sprain or repeated episodes of ankle giving way in the affected limb.
• Subjective ankle instability, with or without pain, swelling, or activity limitation.
• Reduced balance ability, movement ability, or foot and ankle function on screening assessment.
• Symptoms lasting at least 6 months.
• No recent structured ankle rehabilitation before enrollment.
• No plan for vigorous additional exercise during the intervention period.
• Willing to participate and able to provide informed consent.

You may not qualify if…

• Latex allergy or intolerance to floss band material.
• Previous ankle dislocation, fracture, complete ligament rupture, or other severe structural injury.
• Most recent ankle sprain within 1 month before enrollment.
• Recent ankle surgery or acute ankle injury.
• Receipt of other ankle-related treatment, rehabilitation, or additional training during the study period.
• Diabetes, hyperlipidemia, or other conditions that may affect vascular status.
• Neurological disease, major musculoskeletal disease, vestibular disorder, visual disorder, or other lower-limb conditions that could affect assessment.
• Determined by the study physician or investigator to be unsuitable for participation.

Where it is running

• Chengdu Sport University — Chengdu, Sichuan, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.