MMS, IFA, and MMS+IFA Supplementation in Pregnant Women
Starting soon · Not applicable
Conditions studied: Maternal Anemia, Micronutrient Deficiency, Pregnancy Outcomes, Maternal Nutrition
In brief
This study aims to compare the effectiveness of Multiple Micronutrient Supplementation (MMS), Iron-Folic Acid (IFA) supplementation, and combined MMS+IFA supplementation among pregnant women. Maternal anemia and micronutrient deficiencies are common during pregnancy and can adversely affect both maternal and neonatal health outcomes. A total of 402 pregnant women with gestational age of 20 weeks or less will be randomly assigned to receive MMS, IFA, or combined MMS+IFA supplementation. Participants will be followed throughout pregnancy until delivery. Maternal hemoglobin levels, maternal compliance with supplementation, and neonatal outcomes including birth weight, preterm birth, APGAR scores, and congenital anomalies will be assessed. The findings of this study will provide evidence to guide antenatal nutrition policies and practices in Pakistan.
Key facts
- Study ID
- NCT07665957
- Run by
- Sindh Institute of Child Health and Neonatology
- People needed
- 402
- Starts
- 2026-06-25
- Expected to finish
- 2027-01-25
- Last updated by the study team
- 2026-07-01
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- Pregnant women aged 18 years or older
- Gestational age ≤20 weeks at enrollment
- Singleton pregnancy
- Hemoglobin concentration ≥10 g/dL at baseline
- Willing and able to provide informed consent
- Willing to comply with study procedures and follow-up visits
You may not qualify if…
- Severe anemia requiring injectable treatment (hemoglobin <7 g/dL)
- Pre-existing diabetes mellitus
- Pre-existing hypertension
- Renal disease
- Current therapeutic iron or micronutrient supplementation beyond routine antenatal supplementation
- Known fetal congenital anomalies
- Any medical condition that, in the opinion of the investigator, would interfere with study participation or outcome assessment
Full record on ClinicalTrials.gov
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