Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis

Recruiting now · Not applicable

Conditions studied: Knee Osteoarthritis

In brief

The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.

Key facts

Study ID

NCT07664371

Run by

Tanta University

People needed

30

Starts

2026-06-10

Expected to finish

2026-11-01

Last updated by the study team

2026-07-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adults between the ages of 30 and 70 years with a clinical diagnosis of refractory knee OA who suffered from knee pain.
• Patients who cannot afford intra-articular injections.
• patients who had failed 2 different oral pain medications, and 6 weeks of physical therapy.

You may not qualify if…

• Patients with OA show improvement in pain after physiotherapy.
• patients evaluated by an orthopedic surgeon and deemed to be surgical candidates due to knee pathologies other than OA.
• pregnant patients.
• patients on anticoagulation therapy, who were not permitted to stop anticoagulation.
• patients with previous trauma, neurological or endocrine diseases like diabetes mellitus, and knee tumors; and patients with inflammatory arthritis.
• people who had received an intra-articular knee injection within the last 6 months.
• Patients with tendon tears, bursitis, or calcified tendonitis as proven by imaging.

Where it is running

• Faculty of medicine, Tanta University — Tanta, Egypt (enrolling)

Full record on ClinicalTrials.gov

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