NCMT Technique and Jodhpur Technique and Excimer Laser in Treatment of Non Vitiligo Leucoderma

Starting soon · Not applicable

Conditions studied: Leukoderma

In brief

This study aims to compare the efficacy and safety of Melanocyte Keratinocyte Transplantation Procedure (MKTP) combined with 308-nm excimer laser versus Jodhpur technique combined with 308-nm excimer laser in the treatment of stable non-vitiligo leukoderma. Twenty-two patients with stable depigmented lesions will be enrolled. In each patient, two comparable lesions will be treated using different techniques. Clinical outcomes including percentage of repigmentation, color match, time to onset of repigmentation, complications, and histological changes will be assessed during follow-up to determine the optimal surgical treatment approach for non-vitiligo leukoderma.

Key facts

Study ID

NCT07662915

Run by

Al-Azhar University

People needed

22

Starts

2026-07-01

Expected to finish

2027-09-01

Last updated by the study team

2026-06-23

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 to 60 years.
• Clinically diagnosed stable non-vitiligo leukoderma.
• Stable lesion(s) for at least 6 months with no progression.
• Inadequate response to conventional medical therapy.
• Presence of two comparable lesions
• Willingness to participate and provide written informed consent.

You may not qualify if…

• Vitiligo or suspected active vitiligo.
• History of keloid or hypertrophic scar formation.
• Active infection at donor or recipient sites.
• Bleeding disorders or anticoagulant therapy that cannot be safely discontinued.
• Pregnancy or lactation.
• Immunosuppression or uncontrolled systemic disease.
• Inability to comply with follow-up visits.
• Unrealistic expectations regarding treatment outcome.

Full record on ClinicalTrials.gov

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