High-Intensity Laser Therapy (HILT) in Patients With Knee Osteoarthritis

Starting soon · Not applicable · Has a placebo group

Conditions studied: Knee Osteoarthritis (Knee OA)

In brief

This randomized placebo-controlled trial aims to evaluate the effectiveness of High-Intensity Laser Therapy (HILT) as an adjunct to standard outpatient physiotherapy in patients with knee osteoarthritis. Seventy-two participants will be randomly assigned to receive either conventional physiotherapy combined with active HILT or conventional physiotherapy combined with sham HILT. Outcomes related to pain, knee function, physical performance, muscle strength, range of motion, psychosocial factors, quality of life and body composition will be assessed at baseline, after the intervention, and at 8-week follow-up.

Key facts

Study ID

NCT07661407

Run by

University of Rzeszow

People needed

72

Starts

2026-07-03

Expected to finish

2028-03-31

Last updated by the study team

2026-06-29

Who can join

Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Radiographically confirmed knee osteoarthritis
• Mild-to-moderate disease severity
• Pain ≥4 on VAS for at least 3 months
• Ability to participate in physiotherapy
• Informed consent

You may not qualify if…

• Advanced OA requiring surgery
• Previous knee arthroplasty
• Knee instability
• Acute inflammation
• Neurological disorders affecting gait
• Neuropathies or myopathies
• Active inflammatory arthritis
• Recent lower-limb injury (<6 months)
• Intra-articular injections within 3 months
• Cancer, pregnancy, epilepsy
• Electronic implants or pacemaker
• Active local infection

Full record on ClinicalTrials.gov

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