Brief Bronchial Suction for Lung Collapse During Uniportal VATS
Starting soon · Not applicable
Conditions studied: Lung Collapse, One-lung Ventilation, Thoracic Anesthesia, Thoracic Surgery, Video-assisted, Double-lumen Tube, Uniportal Video Assisted Thoracic Surgery (U-VATS), Postoperative Pulmonary Complications
In brief
The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery (UVATS). This type of surgery is performed through a small incision in the chest, and good lung collapse helps the surgeon see and work safely. The main questions it aims to answer are 1. Does brief bronchial suction improve the quality of lung collapse 1 minute after chest cavity is opened? 2. Does brief bronchial suction help reach satisfactory lung collapse faster? Researchers will compare patients who receive brief bronchial suction and those who do not. This is to see if suction improves and fastens lung collapse, reduce the need for additional steps if lung is not adequately collapsed, affect inflammation, oxygenation, postoperative pulmonary complications, operative time, and the duration of one-lung ventilation. Participants will 1. Undergo UVATS under general anesthesia 2. Have a double-lumen breathing tube placed as part of the standard anesthetic care 3. Be randomly assigned to either receive bronchial suction for one minute or receive no bronchial suction 4. Have the surgical team assess the quality of lung collapse at different time points 5. Have blood samples taken for interleukin-6, a marker related to inflammation, once during and once after surgery. These samples are collected through a small tube in a vein that is placed as a standard anesthetic care while the participant is under general anesthesia. No extra puncture is required for blood collection. 6. Have information collected from the routine anesthesia and surgical records such as oxygen levels during surgery, length of surgery and lung-related complications within 7 days after surgery
Key facts
- Study ID
- NCT07660588
- Run by
- Mahidol University
- People needed
- 100
- Starts
- 2026-08-01
- Expected to finish
- 2028-07-01
- Last updated by the study team
- 2026-06-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age ≥ 18 years old
- BMI ≤ 35 kg/m2
- American Society of Anesthesiologists (ASA) physical status I to III
- Scheduled for elective single-port video-assisted thoracoscopic surgery (VATS) at Siriraj Hospital
- Requirement for one-lung ventilation using a double-lumen tube (DLT)
- Surgery performed in the lateral decubitus position
- Ability to provide written informed consent
You may not qualify if…
- Previous thoracic surgery
- Known or suspected severe pleural adhesions based on preoperative imaging or clinical history
- Tracheobronchial anatomical abnormalities
- Pulmonary bullae identified on chest radiography or computed tomography, or a history of recurrent pneumothorax
- Forced vital capacity (FVC) < 50% of predicted
- Pregnancy
Where it is running
- Siriraj Hospital, Mahidol University — Bangkok, Thailand
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.