Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery

Starting soon · Not applicable

Conditions studied: Nasal Surgery, Anesthesia, Controlled Hypotension for Nasal Surgeries

In brief

This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods. The study evaluates hemodynamic stability, surgical field quality (Fromme-Boezaart score), tissue perfusion, intraoperative blood loss, surgeon satisfaction, and perioperative adverse effects.

Key facts

Study ID

NCT07660562

Run by

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

People needed

44

Starts

2026-06-25

Expected to finish

2026-07-15

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age > 18 years
• ASA physical status I-II
• Scheduled for elective nasal surgery
• No known serious cardiovascular, respiratory, renal, or hepatic disease
• No known allergy to remifentanil or nicardipine
• No chronic use of beta-blockers, calcium channel blockers, or antihypertensive agents
• Not pregnant or breastfeeding
• BMI ≤ 35 kg/m²
• No emergency surgical indication
• Written informed consent obtained

You may not qualify if…

• Age < 18 years
• ASA III or above
• Known serious cardiovascular, respiratory, renal, or hepatic disease
• Known allergy to remifentanil or nicardipine
• Chronic use of beta-blockers, calcium channel blockers, or antihypertensive agents
• Pregnancy or breastfeeding
• Morbid obesity (BMI > 35 kg/m²)
• Emergency surgery
• Refusal to participate

Full record on ClinicalTrials.gov

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