HoLEP Sexual Survivorship

Enrolling by invitation

Conditions studied: BPH, Lower Urinary Tract Symptoms

In brief

The objective of this study is to evaluate how sexual function, ejaculatory function, and overall sexual satisfaction change following Holmium Laser Enucleation of the Prostate (HoLEP). In doing so, the study team will examine the trade-off between relief of lower urinary tract symptoms and changes in sexual function.

Key facts

Study ID

NCT07660068

Run by

Northwestern University

People needed

252

Starts

2026-06-01

Expected to finish

2029-06-01

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older, up to 100. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Males 18-100 years old
• Electing to undergo HoLEP for the treatment of bothersome lower urinary tract symptoms
• Currently have present antegrade ejaculation (the standard, male ejaculatory process where semen is propelled forward and out through the urethra during orgasm).

You may not qualify if…

• Patients with any of the following:
• Indwelling urinary catheter prior to surgery
• Neurological disease
• History of prior prostatic/urethral surgery that may impact ejaculation
• Patients who lack decisional capacity
• Patients unable to read, understand, and speak English

Where it is running

• Northwestern University — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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