Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease

Starting soon

Conditions studied: Breast Cancer, Quality of Life, Breast Cancer, Metastatic, Breast Cancer, Metastatic Breast Cancer, Leptomeningeal Metastasis of Breast Cancer, Brain Metastases From Breast Cancer

In brief

Central nervous system (CNS) metastases including breast cancer brain metastases (BCBMs) and leptomeningeal disease (LMD) are common affecting up to 30% of patients with metastatic breast cancer (MBC). The goal of this research is to understand symptom burden and quality of life trajectories in this population and how treatments guide care management decisions.

Key facts

Study ID

NCT07659652

Run by

University of California, San Francisco

People needed

200

Starts

2026-06-15

Expected to finish

2035-12-31

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Be male or female 18 years of age or older.
• Have stage 4 (metastatic) breast cancer with spread to the brain parenchyma and/or leptomeninges.
• Have the intention to start or continue anticancer therapy.
• Be able to provide informed consent.
• Be able to speak and read English.

You may not qualify if…

• Participants who are not on any anticancer therapy and are not planning to start any anticancer therapy will be excluded from the study.

Where it is running

• University of California, San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

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