Fospropofol Disodium Versus Propofol for Patient Satisfaction in Ureteroscopy
Starting soon · Phase 4
Conditions studied: Anesthesia for Urologic Endoscopic Surgery, Urinary Calculi
In brief
This single-center single-blind randomized trial compares fospropofol disodium and propofol for anesthesia in elective ureteroscopy patients. A total of 190 eligible adults will be randomly divided into two groups at 1:1 ratio with identical intraoperative maintenance protocols. The primary outcome is 24-hour postoperative anesthesia satisfaction assessed by ISAS scale; secondary and safety endpoints include injection pain, intraoperative hemodynamic events and various perioperative adverse reactions. This study explores the clinical efficacy and safety of the two sedatives to guide rational clinical medication.
Key facts
- Study ID
- NCT07659132
- Run by
- Shiyou Wei
- People needed
- 190
- Starts
- 2026-06-26
- Expected to finish
- 2026-09-26
- Last updated by the study team
- 2026-06-24
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Undergoing elective ureteroscopic surgery
- Aged between 18 and 90 years old
- American Society of Anesthesiologists (ASA) physical status classification grade I to III
You may not qualify if…
- Known allergy to propofol, fospropofol or their excipients
- Severe cardiopulmonary insufficiency
- Hepatic and renal dysfunction.Hepatic or renal insufficiency. Hepatic dysfunction: alanine aminotransferase (ALT) > 50 U/L, or aspartate aminotransferase (AST) > 40 U/L, or total bilirubin (TBIL) ≥ 19 μmol/L; Renal dysfunction: serum creatinine (Cr) > 112 μmol/L, or blood urea nitrogen (BUN) > 7.1 mmol/L, or receiving dialysis within 28 days before surgery.
- Pregnancy, lactation, potential pregnancy or planned pregnancy
- Subjects who refuse to participate
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.