The Role of Carbohydrate Blends and Electrolytes on Physical and Mental Performance During Cycling in the Heat

Starting soon · Not applicable · Has a placebo group

Conditions studied: Hydration, Dehydration (Physiology), Performance

In brief

The aim of the present study is to evaluate the effectiveness of a milk permeate-based sports drink on hydration, carbohydrate oxidation, exercise performance, vigilance, and reaction time in the heat. We anticipate that the milk permeate, with 44 g per liter and high sodium and potassium, will lead to better hydration, energy delivery, and physical and cognitive performance.

Key facts

Study ID

NCT07658820

Run by

Arizona State University

People needed

14

Starts

2026-06-22

Expected to finish

2027-12-31

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy and injury free (muscle, skeletal) for greater than 2 months
• Active cyclists who train at least 3 times per week
• Body mass index (BMI) range of 18.5-30 kg/m2
• VO₂max ≥ 51 mL/kg/min for male participants
• VO₂max ≥ 45 mL/kg/min for female participants

You may not qualify if…

• Taking medicine influences the cardiovascular system
• non-steroidal anti-inflammatory drugs during the last week
• Cancer Diagnosis during the last 5 years
• Current Pregnancy
• History of renal disease, hypertension, obstructive gastrointestinal tract disease, disorders or impairment of the gag reflex, previous gastrointestinal surgery
• History of heat stroke
• Use of testosterone therapy
• Adults who are unable to consent (impaired decision-making capacity)
• Adults having Felinization of the esophagus
• Adults who will undergo Nuclear Magnetic Resonance (NMR) or MRI scanning within 3 days of swallowing a temperature sensitive pills

Where it is running

• 850 Phoenix Bioscience Core — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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