Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During CABG Surgeries in Egyptian Patients.
Starting soon · Phase 4
Conditions studied: Surgical Site Infection (SSI)
In brief
A randomized controlled trial on adults who underwent coronary artery bypass grafting (CABG) surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT) cefazolin administration in preventing surgical site infection in the CABG population. Eligible patients will be randomized using a block design into 2 groups: intervention and control. The intervention group will use continuous infusion of cefazolin (CI), while the control group will follow the traditional presurgical prophylaxis protocol of intermittent cefazolin doses (INT).
Key facts
- Study ID
- NCT07658378
- Run by
- Helwan University
- People needed
- 100
- Starts
- 2026-07-01
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-06-24
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Cardiothoracic ICU-admitted patients who underwent CABG on CPB.
You may not qualify if…
- Patients who require reoperation within 30 days.
- Immunosuppressant patients.
- Patients who are not adherent to the protocol time or dosing, either preoperatively, during, or postoperatively.
- Pregnancy or breastfeeding.
- Patients who refused to sign the informed consent.
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.