Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.
Recruiting now · Not applicable
Conditions studied: Hemifacial Microsomia, Mucormycosis, Oral Squamous Cell Carcinoma, Microgenia, Facial Asymmetry, Fibrous Dysplasia
In brief
This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention. Eligible participants will undergo preoperative clinical assessment and radiological imaging to design customized implants using computer-aided design (CAD) and 3D printing technology. The implants will be fabricated from medical-grade titanium and surgically placed according to standardized maxillofacial reconstructive protocols. Postoperative follow-up will assess functional outcomes, implant stability, complication rates, and aesthetic improvement over a defined observation period. Outcome evaluation will include clinical examination and patient-reported satisfaction measures. The objective of this study is to determine whether patient-specific 3D-printed titanium implants provide reliable functional restoration and improved aesthetic outcomes in facial reconstruction compared to conventional reconstructive techniques.
Key facts
- Study ID
- NCT07654647
- Run by
- Latakia University
- People needed
- 30
- Starts
- 2026-04-26
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-06-17
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 years or older.
- Presence of facial bone defects resulting from cystic or tumoral osteolytic lesions.
- Acquired or congenital facial deformities associated with bony defects or facial asymmetry.
- Patients requiring patient-specific 3D-printed titanium implants for maxillofacial reconstruction.
- Aesthetic indications requiring custom facial implant design, including microgenia (chin retrusion).
- Ability to provide written informed consent.
You may not qualify if…
- Active pathological lesions at the time of enrollment.
- Age below 18 years.
- History of radiotherapy within 12 months prior to enrollment.
- Chronic untreated vitamin D deficiency.
- Uncontrolled diabetes mellitus.
- Inability or unwillingness to comply with follow-up requirements.
Where it is running
- Ahmad Fayez Ahmad — Latakia, Syria (enrolling)
Full record on ClinicalTrials.gov
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